CBD, Cannabis And PsychosisJune 26, 2022
Today we are talking about CBD, cannabis and psychosis and how I’ve used it in patients who may be at risk with psychosis and what to actually avoid.
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Partial Video Transcript:
So the relationship between CBD, cannabis and psychosis in general usually high THC cannabis in psychosis is a really complex one and the research we have coming out so far has been done in actually recreational smoked cannabis that is very high THC so the stuff that gets you really high and very low CBD so the stuff that’s potentially mood balancing so this is the first problem with the research we have is it’s not an accurate picture of how we use medical cannabis how I would use it as a medicine and it doesn’t tell us anything about CBD so the first thing that I usually tell patients who may be a risk of psychosis or of mania or bipolar is that they should really avoid THC because THC in some vulnerable people and again this is just a very small proportion of people who would use THC even high doses of THC may make them more likely to tip over into a psychotic episode or into a bipolar manic episode again it’s still a very low risk but it’s a potential risk if they’re genetically predisposed and if they have other risk factors like a family history for example or they’ve had an episode of mania in the past or they’ve had an episode of psychosis in the past so in general I just tell those people really to avoid THC on the other hand we have CBD CBD has actually been shown in multiple studies to have an T psychosis properties so that means it might help imbalance mood in people who may be treated disposed to psychosis and people who actually already have schizophrenia and psychosis and manic episodes it may actually help them be used as a treatment for their episodes and potentially as a longer-term treatment in schizophrenia there was one side of that paired one of the main drugs used in schizophrenia one of the anti-psychotic drugs to CBD and actually both were shown to have an antipsychotic effect on the brain areas involved in schizophrenia psychosis but CBD actually had a much better scientific profile than some of those other medications so right now we don’t know enough to say that CBD alone can be used as a treatment for schizophrenia but certainly has a lot of promise in that area so if someone has a history of psychosis or bipolar Armenia I usually still tell them it’s probably pretty safe for them to use CBD and it may actually even help their condition so the safest form of CBD for someone who has a genetic predisposition to use would be CBD from hemp in a combination that has less than 0.2 or 0.3 percent THC so a really really good quality CBD oil made to from suitable grade standards made it’s a medicine but really really low in THC even oils CBD oils that are produced for the medical market in Canada for example sometimes that I have up to one percent of of THC and really really high CBD are probably still pretty safe but again the lower this the THC content probably the better in the safer to make matters more complicated there was actually a really interesting study that looked at people who are already diagnosed with schizophrenia or bipolar disorder so bipolar one with manic episodes and then they look to see who smoked cannabis so this is against smoking recreational high THC cannabis and who didn’t and what they actually found was really interesting when they put these people into a brain scanner and functional MRI machine they found that the people who smoked cannabis even the high THC cannabis and again these are people with already have schizophrenia and bipolar